Vercelino R

ORCID: 0000-0003-2854-5769 · 1 paper in corpus

2014

Melatonin analgesia is associated with improvement of the descending endogenous pain-modulating system in fibromyalgia: a phase II, randomized, double-dummy, controlled trial.

BMC pharmacology & toxicology ·doi:10.1186/2050-6511-15-40

BackgroundCentral disinhibition is a mechanism involved in the physiopathology of fibromyalgia. Melatonin can improve sleep quality, pain and pain threshold. We hypothesized that treatment with melatonin alone or in combination with amitrip…