Research questionWhat is the potential role of immune cells and their inflammatory cytokines in the pathogenesis, development and establishment of endometriosis?DesignPeritoneal fluid from 59 women (43 with endometriosis and 16 controls) wh…
PurposeSuperficial peritoneal endometriotic (pEM) lesions are composed of endometrial glands and stroma, in addition to a third component-myofibroblasts and smooth muscles (SM)-like cells. The latter develops secondary to a metaplasia. In t…
BackgroundAdenomyosis (AM) uteri exhibit hyperperistalsis. The latter causes a chronic tissue trauma at the endometrial-myometrial junctional zone (EMJZ). Upon tissue trauma, microdehiscences in the myometrium facilitate the translocation o…
ObjectiveTo determine if ultrastructural tissue trauma occurs in the junctional zone in uteri in adenomyosis.DesignA case-control experimental study.SettingEndometriosis research center.Patient(s)Twelve uteri with adenomyosis, and 9 uteri w…