Ruochan Chen

No ORCID on file · 2 papers in corpus

review 2026

DAMP signaling networks: from receptors to diverse pathophysiological functions

Journal of Advanced Research ·doi:10.1016/j.jare.2025.07.047

BACKGROUND: Damage-associated molecular patterns (DAMPs) are endogenous molecules released or exposed during cellular stress, injury, or death. Initially characterized as danger signals that alert the immune system, DAMPs are now recognized…

review 2025

Pattern recognition receptors: function, regulation and therapeutic potential

Signal transduction and targeted therapy ·doi:10.1038/s41392-025-02264-1

Pattern recognition receptors (PRRs) are sensors in the immune system, detecting pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). They serve as essential links between the innate and adaptive …