Wadelius C

No ORCID on file · 2 papers in corpus · active 2016-2019
2019
Detailed Functional Characterization of a Waist-Hip Ratio Locus in 7p15.2 Defines an Enhancer Controlling Adipocyte Differentiation.
iScience ·doi:10.1016/j.isci.2019.09.006

We combined CAGE sequencing in human adipocytes during differentiation with data from genome-wide association studies to identify an enhancer in the SNX10 locus on chromosome 7, presumably involved in body fat distribution. Using reporter a…

2016
Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression.
Human genetics ·doi:10.1007/s00439-016-1654-x

Genome-wide association studies (GWAS) have identified a large number of disease-associated SNPs, but in few cases the functional variant and the gene it controls have been identified. To systematically identify candidate regulatory variant…