Jian-Zhong Sheng — Endo Lab

article 2016

Hyaluronic acid reagent functional chitosan-PEI conjugate with AQP2-siRNA suppressed endometriotic lesion formation

International journal of nanomedicine ·doi:10.2147/ijn.s99692

To identify a new drug candidate for treating endometriosis which has fewer side effects, a new polymeric nanoparticle gene delivery system consisting of polyethylenimine-grafted chitosan oligosaccharide (CSO-PEI) with hyaluronic acid (HA) …

review 2012

Functions of water channels in male and female reproductive systems

Molecular aspects of medicine ·doi:10.1016/j.mam.2012.02.002

Twelve water channels (aquaporins) are expressed in mammalian reproductive systems, and play very important roles in maintaining water homeostasis in reproductive cells. Impairment of their functions can result in attenuated male and female…

other 2011

Identification of estrogen response element in the aquaporin-2 gene that mediates estrogen-induced cell migration and invasion in human endometrial carcinoma

The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2011-0426

BACKGROUND: Accumulating evidence suggests that aquaporins (AQP) can facilitate cell migration, invasion, and proliferation in tumor development in addition to water transport. OBJECTIVE: The aim of this study was to examine AQP2 expressio…

article 2007

Increased expression of c-fos protein associated with increased matrix metalloproteinase-9 protein expression in the endometrium of endometriotic patients

Fertility and sterility ·doi:10.1016/j.fertnstert.2007.07.1386

ObjectiveTo investigate c-fos and matrix metalloproteinase-9 (MMP-9) expression in the endometrium from women with or without endometriosis throughout the menstrual cycle, and to explore the correlation of c-fos expression with MMP-9 expres…

article 2004

Matrix metalloproteinase 2 is associated with changes in steroid hormones in the sera and peritoneal fluid of patients with endometriosis

Fertility and sterility ·doi:10.1016/j.fertnstert.2003.10.027

ObjectiveTo determine matrix metalloproteinase 2 (MMP-2) levels in sera and peritoneal fluids of women with or without endometriosis-associated infertility and to determine whether MMP-2 had correlation with 17beta-E(2) and P in the sera an…