Jongyoon Han

No ORCID on file · 2 papers in corpus · active 2012-2013

Study types

  • article 2

Condition tags

  • endometriosis 2
article 2013
ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.1222387110

A Disintegrin and Metalloproteinases (ADAMs) are the principal enzymes for shedding receptor tyrosine kinase (RTK) ectodomains and ligands from the cell surface. Multiple layers of activity regulation, feedback, and catalytic promiscuity im…

article 2012
Multiplexed Protease Activity Assay for Low-Volume Clinical Samples Using Droplet-Based Microfluidics and Its Application to Endometriosis
Journal of the American Chemical Society ·doi:10.1021/ja307866z

As principal degrading enzymes of the extracellular matrix, metalloproteinases (MPs) contribute to various pathologies and represent a family of promising drug targets and biomarker candidates. However, multiple proteases and endogenous inh…