OBJECTIVE: To perform a preliminary, hypothesis-generating evaluation of the association between intraovarian injection of platelet-rich plasma (PRP) combined with peripheral blood mononuclear cells (PBMCs) and ovarian response parameters i…
BACKGROUND: In clinical practice, repeated oocyte retrieval cycles are often necessary for patients with diminished ovarian reserve (DOR). It has been hypothesized that the mechanical stimulation from the initial oocyte pick-up (OPU) proced…
BACKGROUND: Information on the impact of Progestin-primed ovarian stimulation (PPOS) protocol on embryo euploid status and preimplantation genetic testing for aneuploidy (PGT-A) outcomes is limited compared with other ovarian stimulation pr…
BACKGROUND: The sirtuin family is well recognized for its crucial involvement in various cellular processes. Nevertheless, studies on its role in the human endometrium are limited. This study aimed to explore the expression and localization…
The adverse effect of ambient PM2.5 exposure on very early pregnancy (VEP) remains controversial among epidemiological studies but is supported by toxicological evidence. We adopted a multicenter retrospective cohort of 141,040 cycles to ev…
BACKGROUND: We previously reported that obese mice had significantly high lipid content in embryos, and excessive lipids are detrimental to embryonic development. However, whether maternal obesity has an effect on embryonic vitrification in…
The establishment of pregnancy in human necessitates appropriate decidualization of stromal cells, which involves steroids regulated periodic transformation of endometrial stromal cells during the menstrual cycle. However, the potential mol…
BACKGROUND: This meta-analysis summarizes evidence from studies using metformin (Met) to improve endometrial receptivity (ER) in women with PCOS. METHODS: Following the PRISMA protocol, we conducted a comprehensive search of academic liter…
AIM: To compare the expression of estrogen receptor α (ERα), Bcl-2 and NF-κB P65 in endometrial polyps from patients with and without endometriosis. METHODS: Immunohistochemistry was used to characterize the expression of ERα, Bcl-2 and NF…
This meta-analysis aimed to evaluate the variation in the diagnostic criteria for chronic endometritis (CE) and its effect on reproductive outcomes. A search of the academic literature was conducted in various databases including PubMed, Em…