Rådestad AF

No ORCID on file · 3 papers in corpus
other 2026
Individualised progesterone receptor modulator prevention strategies for triple-negative breast cancer in BRCA1 pathogenic variant carriers.
NPJ breast cancer ·doi:10.1038/s41523-026-00998-x

Women with germline BRCA1 pathogenic variants face a very high risk of early-onset triple-negative breast cancer (TNBC), with risk-reducing mastectomy currently the only established preventive option. Emerging evidence suggests aberrant pro…

observational 2026
The cervico-vaginal DNA methylation WID-qEC test: An epigenetic marker associated with ovarian cancer in the absence of endometrial and cervical cancer
International journal of cancer ·doi:10.1002/ijc.70354

The DNA methylation-based WID-qEC test, applied to cervico-vaginal samples, has been validated for the accurate detection of endometrial and cervical cancers. However, a small proportion of women test positive despite the absence of these c…

rct 2022
Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women
Genome medicine ·doi:10.1186/s13073-022-01063-5

BACKGROUND: Breast cancer is a leading cause of death in premenopausal women. Progesterone drives expansion of luminal progenitor cells, leading to the development of poor-prognostic breast cancers. However, it is not known if antagonising …