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Dopamine agonist administration causes a reduction in endometrial implants through modulation of angiogenesis in experimentally induced endometriosis
BACKGROUND: Implantation of a retrogradely-shed endometrium during menstruation requires an adequate blood supply. The endometrium has angiogenic potential, and endometriotic lesions grow in areas with a rich vascularization, suggesting tha…
Survival of newly implanted retrograde–shed endometrial tissue during menstruation in an ectopic location requires an adequate blood supply. This suggests that angiogenesis is a prerequisite for the development of endometriosis and that its…
also sensitized ESC to Fas-mediated apoptosis, but this effect seems not to be mediated by the downregulation of FLIP, an inhibitor of caspase-8 activation. Conclusion: In summary, we demonstrate that human ESC are primarily resistant to ap…