Wang LE

No ORCID on file · 4 papers in corpus
2013
Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk.
Carcinogenesis ·doi:10.1093/carcin/bgs407

Genome-wide association studies (GWASs) have mainly focused on top significant single nucleotide polymorphisms (SNPs), most of which did not have clear biological functions but were just surrogates for unknown causal variants. Studying SNPs…

2013
Association between putative functional variants in the PSMB9 gene and risk of melanoma--re-analysis of published melanoma genome-wide association studies.
Pigment cell & melanoma research ·doi:10.1111/pcmr.12069

To mine possibly hidden causal single-nucleotide polymorphisms (SNPs) of melanoma, we investigated the association of SNPs in 76 M/G1 transition genes with melanoma risk using our published genome-wide association study (GWAS) data set with…

2011
Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3.
Nature genetics ·doi:10.1038/ng.958

We performed a genome-wide association study of melanoma in a discovery cohort of 2,168 Australian individuals with melanoma and 4,387 control individuals. In this discovery phase, we confirm several previously characterized melanoma-associ…

2011
Genome-wide association study identifies novel loci predisposing to cutaneous melanoma.
Human molecular genetics ·doi:10.1093/hmg/ddr415

We performed a multistage genome-wide association study of melanoma. In a discovery cohort of 1804 melanoma cases and 1026 controls, we identified loci at chromosomes 15q13.1 (HERC2/OCA2 region) and 16q24.3 (MC1R) regions that reached genom…