Lambris JD

ORCID: 0000-0002-9370-5776 · 1 paper in corpus

2012

Genetic and pharmacologic inhibition of complement impairs endothelial cell function and ablates ovarian cancer neovascularization.

Neoplasia (New York, N.Y.) ·doi:10.1593/neo.121262

Complement activation plays a critical role in controlling inflammatory responses. To assess the role of complement during ovarian cancer progression, we crossed two strains of mice with genetic complement deficiencies with transgenic mice …