Zembutsu H — Endo Lab

2017

Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases.

Journal of epidemiology ·doi:10.1016/j.je.2016.12.003

BackgroundTo implement personalized medicine, we established a large-scale patient cohort, BioBank Japan, in 2003. BioBank Japan contains DNA, serum, and clinical information derived from approximately 200,000 patients with 47 diseases. Ser…

2017

Overview of the BioBank Japan Project: Study design and profile.

Journal of epidemiology ·doi:10.1016/j.je.2016.12.005

BackgroundThe BioBank Japan (BBJ) Project was launched in 2003 with the aim of providing evidence for the implementation of personalized medicine by constructing a large, patient-based biobank (BBJ). This report describes the study design a…

review 2012

Genome-wide association meta-analysis identifies new endometriosis risk loci

Nature genetics ·doi:10.1038/ng.2445

We conducted a genome-wide association meta-analysis of 4,604 endometriosis cases and 9,393 controls of Japanese and European ancestry. We show that rs12700667 on chromosome 7p15.2, previously found to associate with disease in Europeans, r…

article 2010

A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese

Nature genetics ·doi:10.1038/ng.612

Although the pathogenesis of endometriosis is not well understood, genetic factors have been considered to have critical roles in its etiology. Through a genome-wide association study and a replication study using a total of 1,907 Japanese …