Jianxiong Jiang

No ORCID on file · 2 papers in corpus
lab-animal 2023
Bioorganic & medicinal chemistry letters ·doi:10.1016/j.bmcl.2023.129255

EP2 is a G protein-coupled receptor for prostaglandin E2 (PGE2) derived from cell membrane-released arachidonic acid upon various harmful and injurious stimuli. It is commomly upregulated in tumors and injured brain tissues, as its activati…

review 2013
Trends in pharmacological sciences ·doi:10.1016/j.tips.2013.05.003

Modulation of a specific prostanoid synthase or receptor provides therapeutic alternatives to nonsteroidal anti-inflammatory drugs (NSAIDs) for treating pathological conditions governed by cyclooxygenase-2 (COX-2 or PTGS2). Among the COX-2 …