David H Mvunta

No ORCID on file · 2 papers in corpus

review 2024

Prognostic and clinicopathological significance of survivin in gynecological cancer

Oncology reviews ·doi:10.3389/or.2024.1444008

Survivin belongs to the inhibitor of apoptosis protein (IAP) family and is encoded by the baculoviral inhibitor of apoptosis repeat-containing, or BIRC5, gene. It is preferentially expressed in cancers with functional complexity in cell sig…

observational 2017

Overexpression of SIRT1 is Associated With Poor Outcomes in Patients With Ovarian Carcinoma

Applied immunohistochemistry & molecular morphology : AIMM ·doi:10.1097/PAI.0000000000000316

Sirtuin 1 (SIRT1), originally identified as a longevity gene, regulates DNA repair and metabolism by deacetylating target proteins such as p53. SIRT1 plays a key role in the pathophysiology of metabolic diseases and neurodegenerative disord…