James A. Deane

ORCID: 0000-0001-8409-0303 · 7 papers in corpus · active 2013-2020

Study types

  • review 3
  • other 2
  • preprint 2

Condition tags

  • endometriosis 7
  • mesh:D004715 2
  • adenomyosis 2
  • infertility 1
preprint 2020
·doi:10.21203/rs.3.rs-45953/v2
preprint 2020
·doi:10.21203/rs.3.rs-45953/v1

Abstract Objective: Endometriosis is a common and painful condition characterized by the formation of endometrial lesions within the peritoneal cavity. Previous studies have suggested a role for hedgehog signalling in the pathogenesis of en…

other 2018
Stem cells (Dayton, Ohio) ·doi:10.1002/stem.2706

Studies from five independent laboratories conclude that bone marrow stem cells transdifferentiate into endometrial stroma, epithelium, and endothelium. We investigated the nature of bone marrow-derived cells in the mouse endometrium by rec…

other 2017
Human Reproduction ·doi:10.1093/humrep/dex289

STUDY QUESTION: Is there a specific surface marker that identifies human endometrial epithelial progenitor cells with adult stem cell activity using in vitro assays? SUMMARY ANSWER: N-cadherin isolates clonogenic, self-renewing human endom…

review 2016
Human reproduction update ·doi:10.1093/humupd/dmv051

BACKGROUND: The existence of stem/progenitor cells in the endometrium was postulated many years ago, but the first functional evidence was only published in 2004. The identification of rare epithelial and stromal populations of clonogenic c…

review 2015
Seminars in reproductive medicine ·doi:10.1055/s-0035-1558405

Human endometrial mucosa is a dynamically remodeling tissue, undergoing cyclical morphologic and functional changes in response to fluctuating sex steroid hormones each menstrual cycle during a woman's reproductive life. Postmenopausal endo…

review 2013
Current opinion in obstetrics & gynecology ·doi:10.1097/gco.0b013e32836024e7

PURPOSE OF REVIEW: Stem/progenitor cells are present in human and rodent endometrium and have a key role in endometrial regeneration in normal cycling and after parturition. We review emerging evidence of multiple types of endometrial stem/…