McConechy MK

No ORCID on file · 4 papers in corpus
other 2017
Nature genetics ·doi:10.1038/ng.3849

We studied the whole-genome point mutation and structural variation patterns of 133 tumors (59 high-grade serous (HGSC), 35 clear cell (CCOC), 29 endometrioid (ENOC), and 10 adult granulosa cell (GCT)) as a substrate for class discovery in …

article 2017
Gynecologic Oncology ·doi:10.1016/j.ygyno.2017.09.032

ObjectiveEndometrioid (ENOC) and clear cell ovarian carcinoma (CCOC) share a common precursor lesion, endometriosis, hence the designation endometriosis associated ovarian cancers (EAOC). Long interspersed nuclear element 1 (LINE-1 or L1), …

other 2014
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc ·doi:10.1038/modpathol.2013.107

Ovarian endometrioid carcinomas and endometrial endometrioid carcinomas share many histological and molecular alterations. These similarities are likely due to a common endometrial epithelial precursor cell of origin, with most ovarian endo…

article 2010
New England Journal of Medicine ·doi:10.1056/nejmoa1008433

BACKGROUND: Ovarian clear-cell and endometrioid carcinomas may arise from endometriosis, but the molecular events involved in this transformation have not been described. METHODS: We sequenced the whole transcriptomes of 18 ovarian clear-ce…