Cesar J

No ORCID on file · 3 papers in corpus
2015
PloS one ·doi:10.1371/journal.pone.0117984

Progesterone has a number of important functions throughout the human body. While the roles of progesterone are well known, the possible actions and implications of progesterone metabolites in different tissues remain to be determined. Ther…

other 2011
Journal of medicinal chemistry ·doi:10.1021/jm101104z

17β-Hydroxysteroid dehydrogenase type 1 (17β-HSD1) is an enzyme that catalyzes NADPH-dependent reduction of the weak estrogen, estrone, into the most potent estrogen, estradiol, which exerts proliferative effects via the estrogen receptors.…

other 2009
Chemico-biological interactions ·doi:10.1016/j.cbi.2008.10.019

Human hydroxysteroid dehydrogenase (HSD) AKR1C1 is a member of the aldo-keto reductase superfamily, and it functions mainly as a 20alpha-HSD. It catalyzes the reduction of the potent progesterone to the weak 20alpha-hydroxyprogesterone, and…