Hongjie Ruan

ORCID: 0000-0001-5318-2037 · 2 papers in corpus
lab-animal 2026
An anti-invasion endogenous tRNA-derived small RNA (3'-tRFAlaAGC) alleviates endometriosis by suppressing MCCC1 mediated EMT
Cellular signalling ·doi:10.1016/j.cellsig.2026.112990

Endometriosis is an invasive gynecological disorder, characterized by occult ectopic endometrial growth. Nascent endogenous tRNA-derived fragments occur across various disease, yet its pathology mechanistic pathways in endometriosis remain …

2025
Safety and efficacy of subcutaneous injection with HMI-115 versus placebo in endometriosis-associated pain in premenopausal women: a multicentre, double-blind, randomised, proof-of-concept phase 2 trial
·doi:10.1016/j.lanogw.2025.100032