Semreen MH

No ORCID on file · 1 paper in corpus

2016

Design, synthesis, and biological evaluation of new arylamide derivatives possessing sulfonate or sulfamate moieties as steroid sulfatase enzyme inhibitors.

Bioorganic & medicinal chemistry ·doi:10.1016/j.bmc.2016.04.040

A series of new arylamide derivatives possessing terminal sulfonate or sulfamate moieties was designed and synthesized. The target compounds were tested for in vitro inhibitory effects against the steroid sulfatase (STS) enzyme in a cell-fr…