目的 探究平冲降逆方(PJR)调控miR-199a-3p/哺乳动物雷帕霉素靶蛋白(mTOR)信号通路治疗子宫内膜异位症(EMs)模型大鼠的潜在机制。 方法 将40只SD雌性大鼠随机分为假手术组、模型组、PJR组及西药组。假手术组未移植内膜仅接受开腹操作,EMs大鼠模型行自体子宫内膜移植手术构建,造模成功后灌胃给药,PJR组予PJR煎剂(7.56 g·kg⁻¹),西药组予孕三烯酮混悬液(0.26 mg·kg⁻¹),假手术组和模型组予等量生理盐水,持续21天。取材测量异位病灶的质…
The Ping-Chong-Jiang-Ni Formula (PCJNF), a compound of Traditional Chinese Medicine (TCM), has demonstrated remarkable clinical effectiveness and is widely utilized in the treatment of endometriosis (EMs). Previous studies have shown that P…
ETHNOPHARMACOLOGICAL RELEVANCE: Pingchong Jiangni recipe (PJR) is often used in the treatment of endometriosis (EM). This formula has been clinically validated by the State Administration of Traditional Chinese Medicine Key Specialties Coll…
Colorectal cancer (CRC) is one of the most common malignant carcinomas in the world, and metastasis is the main cause of CRC-related death. However, the molecular network involved in CRC metastasis remains poorly understood. Long noncoding …