Li J

In the surgical treatment of deep infiltrating endometriosis, the completeness of lesion removal is crucial for the success of the procedure. Consequently, an array of auxiliary surgical methods are continuously being refined to improve the…

RATIONALE: Ureteral injury from sutures during total hysterectomy is a relatively uncommon but potentially severe complication that can lead to serious sequelae such as ureterovaginal fistula or renal insufficiency. The management of such i…

Tryptophan (Trp) is one of the essential amino acids, and its metabolic pathway is essential for the maintenance of normal human physiological activities. Among them, various metabolites and rate-limiting enzymes of the tryptophan-kynurenin…

PURPOSE: Hydrosalpinx reduces the pregnancy outcomes of in vitro fertilization and embryo transfer (IVF-ET). Tubal occlusion has been shown to improve IVF-ET success; however, the optimal timing of oocyte retrieval and the molecular changes…

This study introduces a novel "tunnel method" for single-position laparoscopic nephroureterectomy in women with upper urinary tract urothelial carcinoma (UTUC), enabling complete resection of the kidney and entire ureter while preserving th…

INTRODUCTION: Raising the temperature of abdominal wall endometriosis lesions contributes to an effective ablation; however, providing sufficient protection to the surrounding tissues remains a challenge. In this study, we aimed to combine …

Despite intensive development, P2X7 modulators have struggled in translation due to human genetic variability and species-dependent drug responses. Here, we identify PSFL1191, a portal-of-central-pocket (PCP)-site inhibitor selective for hu…

Autoimmune pancreatitis (AIP) is identified as a severe chronic immune-related disorder in pancreas, including two subtypes. In this study, pancreatic lesions in patients diagnosed as either type 1 AIP or type 2 AIP are examined, and these …

BackgroundOvarian aging is the main cause of reduced reproductive life span, yet its metabolic profiles remain poorly understood. This study aimed to reveal the metabolic homogeneity and heterogeneity between physiological and pathological …

In β‑thalassemia, excessive α‑globin chain impedes the normal development of red blood cells resulting in anemia. Numerous miRNAs, including miR‑6747‑3p, are aberrantly expressed in β‑thalassemia major (β‑TM), but there are no reports on th…

BACKGROUND: Women diagnosed with adenomyosis often suffer from infertility and frequently seek assisted reproductive techniques (ART). It remains unclear whether certain patients possess the potential to achieve spontaneous pregnancy. This …

Ovarian cancer remains the most lethal malignancy of the female reproductive tract. Because early-stage disease is almost silent, roughly 70% of patients present with advanced, disseminated tumors. The current standard-maximal cytoreductive…

Background: Abnormal uterine bleeding (AUB) is a problem that affects women and can cause outcomes such as anaemia, affecting women's quality of life. In high-performance athletes, this problem can be further exacerbated by intense physical…

Ureteral endometriosis accounts for about 5 % of urologic endometriosis, with a peak incidence in the age group of 30-35 years, usually with unilateral onset. Because of its insidious onset, often combined with asymptomatic loss of renal fu…

Endometrial cancer (EC) is the sixth most detected cancer and the 14th most prevalent cause of cancer death in women globally, affecting 2.8% of women at some point in their lifetime1. Patients typically present with uterine-confined pathol…

Growing evidence suggests that perfluorinated compounds (PFCs) contribute to reproductive toxicity, with perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) being the most extensively studied. These chemicals are known to low…

Mucinous ovarian carcinoma (MOC) is a subtype of ovarian cancer that is distinct from all other ovarian cancer subtypes and currently has no targeted therapies. To identify novel therapeutic targets, we developed and applied a new method of…

Huali Fei,1 Xiaoyan Guo,2 Jin Li,2 Xuejing Jin1 1Department of Reproductive Endocrinology, Hangzhou Women’s Hospital, Hangzhou, People’s Republic of China; 2Department of Gynecology, Hangzhou Women’s Hospital, Hangzhou, People’s Republic of…

OBJECTIVE: To report a rare case of multiple subserous uterine adenomyomas diagnosed and treated by laparoscopy. CASE REPORT: A premenopausal 55-year-old woman was admitted presenting with bilateral adnexal cysts. Preoperative ultrasound a…

ObjectiveVery few and conflicting data are available regarding the correlation between circulating carbohydrate antigen 19-9 (CA19-9) levels and diabetic kidney disease (DKD) and its components including albuminuria and a low estimated glom…

BackgroundExposure to metal could impact women's depression risk. However, the connection and mechanisms between metalloestrogens exposure and depression are still not fully understood. We aim to explore the associations between metalloestr…

ObjectiveThis study investigates the relationship between cardiovascular health (CVH), as quantified by the American Heart Association's Life's Essential 8 (LE8) metric, and female infertility, utilizing data from the National Health and Nu…

BackgroundEvidence indicates that the risk of developing a secondary ovarian cancer (OC) is correlated with estrogen receptor (ER) status. However, the clinical significance of the relationship between ER-associated breast cancer (BC) and c…

BACKGROUND: Endometriosis is a chronic inflammatory disease of women during their reproductive years. The relationship between the severity and location of endometriosis and menstruation, ovulation, reproductive function, and mode of delive…