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Primordial germ cells (PGCs) are the embryonic precursors of the gametes. In rodents, PGCs readily form self-renewing embryonic germ cell (EGC) lines in vitro. Although human PGCs undergo a similar conversion during germ cell tumorigenesis,…

Appendicitis is a very common indication for surgery, although in recent years uncomplicated cases have often been managed with antibiotics. In this case, we discuss a patient who presented to the emergency department with a case of seeming…

Catherine is an advanced nurse practitioner working alongside her medical colleagues in a large general practice in the North of England. She receives and treats patients with undifferentiated complaints. Alice, a 30-year-old woman, is ushe…