Vladislav Baranov

No ORCID on file · 5 papers in corpus
other 2023
Pharmaceutics ·doi:10.3390/pharmaceutics15082108

Anti-angiogenic RNAi-based therapy can be considered as a possible strategy for the treatment of endometriosis (EM), which is the most common gynecological disease. Targeted delivery of siRNA therapeutics is a prerequisite for successful tr…

lab-animal 2022
Bioengineering (Basel, Switzerland) ·doi:10.3390/bioengineering9030112

Suicidegene therapy is considered a promising approach for the treatment of uterine leiomyoma (UL), a benign tumor in women characterized by precise localization. In this study, we investigate the efficiency of αvβ3 integrin-targeted argini…

other 2020
Pharmaceuticals (Basel, Switzerland) ·doi:10.3390/ph13100300

Efficient and specific delivery of nucleic acid (NA) therapeutics to tumor cells is extremely important for cancer gene therapy. Various therapeutic strategies include delivery of DNA-therapeutics such as immunostimulatory or suicide genes …

lab-animal 2018
Gene therapy ·doi:10.1038/s41434-018-0042-7

Development of gene therapy for endometriosis requires inhibition of vascularization in endometrial lesions. We have previously developed CXCR4 receptor-targeted siRNA carrier L1 and observed efficient RNAi-mediated down-regulation of VEGFA…

review 2018
International journal of molecular sciences ·doi:10.3390/ijms19071852

For over 100 years, endometriosis, as a chronic, estrogen-dependent, inflammatory, heritable disease affecting approximately 5⁻10% of women in reproductive age has been the focus of clinicians and scientists. In spite of numerous environmen…