Ruofan Huang

No ORCID on file · 2 papers in corpus

lab-animal 2025

SIRT7 drives energy metabolic shifts in endometriosis via interaction with TUFM and Rhoa/Rock/Akt pathway activation

Cellular and molecular life sciences : CMLS ·doi:10.1007/s00018-025-05886-4

PURPOSE: Endometriosis is characterized by the ectopic growth of endometrial-like tissue outside the uterus and altered energy metabolism, but the specific mechanisms involved remain unclear. This study aimed to investigate the impact of Si…

lab-animal 2024

LncRNA PKD1P6 modulates ovarian granulosa cell survival of hyperandrogenic polycystic ovary syndrome by targeting miR-135b-5p and inhibiting ERK1/2 signaling

Heliyon ·doi:10.1016/j.heliyon.2024.e36321

Polycystic ovary syndrome (PCOS) is the most common and multifactorial endocrine disease among women of reproductive age. Aberrant folliculogenesis is a common pathological characteristic of PCOS, but the underlying molecular mechanism rema…