Vahteristo P

No ORCID on file · 4 papers in corpus · active 2014-2025

Study types

  • article 1
  • other 1

Condition tags

  • endometriosis 2
2025
Genomic landscape of endometrial polyps.
Genome medicine ·doi:10.1186/s13073-025-01556-z

BackgroundEndometrial polyps are common, localized overgrowths of endometrial glands and stroma that protrude into the uterine cavity. These tumor-like lesions can cause symptoms like abnormal uterine bleeding and infertility, and they may …

article 2023
Whole-exome sequencing reveals candidate high-risk susceptibility genes for endometriosis
Human genomics ·doi:10.1186/s40246-023-00538-9

BACKGROUND: Endometriosis is a common, chronic disease among fertile-aged women. Disease course may be highly invasive, requiring extensive surgery. The etiology of endometriosis remains elusive, though a high level of heritability is well …

other 2022
TCGA molecular classification in endometriosis-associated ovarian carcinomas: Novel data on clear cell carcinoma
Gynecologic oncology ·doi:10.1016/j.ygyno.2022.03.016

BACKGROUND: Clear cell and endometrioid ovarian carcinomas (OCC and OEC, respectively) have a presumed origin in endometriosis and share molecular alterations with each other and with their endometrial counterparts. The Cancer Genome Atlas …

2014
Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.
Cell reports ·doi:10.1016/j.celrep.2014.03.047

Somatic mutations in exon 2 of the RNA polymerase II transcriptional Mediator subunit MED12 occur at very high frequency (∼70%) in uterine leiomyomas. However, the influence of these mutations on Mediator function and the molecular basis fo…