Anthony Valentijn

No ORCID on file · 7 papers in corpus
lab-animal 2025
Transcriptional Profiling of SSEA-1+ Endometrial Epithelial Progenitor Cells Highlights Their Role in Endometrial Regeneration, Remodeling, and Homeostasis
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.202402861r

Stage-specific embryonic antigen-1 (SSEA-1)+ endometrial epithelial cells (EECs) assume the postulated stem/progenitor cell niche within the human endometrium. Previous studies have demonstrated that isolated SSEA-1+ cells have a higher cap…

observational 2020
Fallopian tube epithelial cells express androgen receptor and have a distinct hormonal responsiveness when compared with endometrial epithelium
Human Reproduction ·doi:10.1093/humrep/deaa177

STUDY QUESTION: How does steroid receptor expression, proliferative activity and hormone responsiveness of the fallopian tube (FT) epithelium compare to that of the endometrial epithelium? SUMMARY ANSWER: Proliferative indices, hormone rec…

other 2018
Abnormally located SSEA1+/SOX9+ endometrial epithelial cells with a basalis-like phenotype in the eutopic functionalis layer may play a role in the pathogenesis of endometriosis
Human Reproduction ·doi:10.1093/humrep/dey336

STUDY QUESTION: Is endometriosis associated with abnormally located endometrial basalis-like (SSEA1+/SOX9+) cells in the secretory phase functionalis and could they contribute to ectopic endometriotic lesion formation? SUMMARY ANSWER: Wome…

observational 2015
Human endometrial epithelial telomerase is important for epithelial proliferation and glandular formation with potential implications in endometriosis
Human Reproduction ·doi:10.1093/humrep/dev267

STUDY QUESTION: How does regulation of telomerase activity (TA) in human endometrial epithelial cells (EEC) by ovarian hormones impact on telomere lengths (TL) and cell proliferation? SUMMARY ANSWER: Healthy endometrial epithelial cell pro…

other 2015
In silico, in vitro and in vivo analysis identifies a potential role for steroid hormone regulation of FOXD3 in endometriosis-associated genes
Human Reproduction ·doi:10.1093/humrep/dev307

STUDY QUESTION: Can bioinformatics analysis of publically available microarray datasets be utilized in identifying potentially important transcription factors (TF) in the hormonal regulation of the endometrium? SUMMARY ANSWER: Systems inte…

observational 2013
Endometriosis, endometrium, implantation and fallopian tube
·doi:10.1093/humrep/det211

Study question: To compare the pregnancy rate in patients submitted to FET (Frozen Embryos Transfer) of cleavage stage embryos (Group 1), or at the blastocyst stage (Group 2). Summary answer: Our data showed that the transfer of frozen blas…

observational 2011
Aberrant expression of metastasis-inducing proteins in ectopic and matched eutopic endometrium of women with endometriosis: implications for the pathogenesis of endometriosis
Human Reproduction ·doi:10.1093/humrep/der412

BACKGROUND: Endometriosis is a metastatic disease without obvious tumorigenesis. Expression of S100P, S100A4, osteopontin (OPN) or anterior gradient homologue 2 (AGR2) proteins can induce metastasis but fail to induce tumorigenesis per se. …