E R Simpson
No ORCID on file
· 5 papers in corpus
· active 1996-2001
Study types
- review 4
- article 1
Condition tags
- endometriosis 5
Top journals
Frequent coauthors
- Serdar E. Bulun 5
- Leslie R. Noble 3
- A Johns 2
- Hironobu Sasano 2
- Ken‐ichi Takayama 2
- Khaled Zeitoun 2
- V Agarwal 1
- Y Ito 1
- Y Zhao 1
- C Fisher 1
review
2001
While the ovaries are the principal source of systemic estrogen in the premenopausal nonpregnant woman, other sites of estrogen biosynthesis are present throughout the body and these become the major sources of estrogen beyond menopause. Th…
review
1999
Cessation of ovarian estrogen secretion is the key event during the climacteric. An enzyme termed aromatase in a number of human tissues and cells, including ovarian granulosa cells, the placental syncytiotrophoblast, adipose and skin fibro…
review
1999
Estrogen is the most important known factor that stimulates the growth of endometriosis. Estrogen delivery to endometriotic implants was classically viewed to be only via the circulating blood in an endocrine fashion. We recently uncovered …
review
1997
Aromatase P450 (P450arom) is responsible for conversion of C19 steroids to estrogens in a number of human tissues, such as the placenta, gonads, adipose tissue, skin and the brain. Aromatase expression in human tissues is regulated by use o…
article
1996
The conversion of C19 steroids to estrogens occurs in a number of tissues, such as the ovary and placenta, and is catalyzed by aromatase P450 (P450arom; the product of the CYP19 gene). P450arom expression has also been detected in a number …