Paul Pharoah

No ORCID on file · 3 papers in corpus · active 2013-2022

Study types

  • meta-analysis 2
  • other 1

Condition tags

  • endometriosis 3
meta-analysis 2022
A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypes
Cell reports. Medicine ·doi:10.1016/j.xcrm.2022.100542

Endometriosis is associated with increased risk of epithelial ovarian cancers (EOCs). Using data from large endometriosis and EOC genome-wide association meta-analyses, we estimate the genetic correlation and evaluate the causal relationshi…

other 2016
Assessment of Multifactor Gene-Environment Interactions and Ovarian Cancer Risk: Candidate Genes, Obesity, and Hormone-Related Risk Factors
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology ·doi:10.1158/1055-9965.EPI-15-1039

BACKGROUND: Many epithelial ovarian cancer (EOC) risk factors relate to hormone exposure and elevated estrogen levels are associated with obesity in postmenopausal women. Therefore, we hypothesized that gene-environment interactions related…

meta-analysis 2013
Combined and interactive effects of environmental and GWAS-identified risk factors in ovarian cancer
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology ·doi:10.1158/1055-9965.EPI-12-1030-T

BACKGROUND: There are several well-established environmental risk factors for ovarian cancer, and recent genome-wide association studies have also identified six variants that influence disease risk. However, the interplay between such risk…