Ji Hyun Park

ORCID: 0000-0002-1534-0070 · 10 papers in corpus
other 2021
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-021-00531-4

Cell membrane ion channels have important roles in cell migration during cancer development and metastasis. Although endometriosis is a benign gynecological disease, some migration and invasion characteristics of endometriosis are similar t…

lab-animal 2021
Clinical and experimental reproductive medicine ·doi:10.5653/cerm.2021.04392

OBJECTIVE: Red ginseng (RG) exerts anti-inflammatory, anti-proliferative, and immunomodulatory effects on endometriosis through the regulation of microRNA (miRNA) expression. It may also ameliorate endometriosis by affecting the expression …

other 2021
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-021-00551-0
review 2021
International journal of molecular sciences ·doi:10.3390/ijms22020823

Mechanistic understanding of germ cell formation at a genome-scale level can aid in developing novel therapeutic strategies for infertility. Germ cell formation is a complex process that is regulated by various mechanisms, including epigene…

lab-animal 2019
International journal of molecular sciences ·doi:10.3390/ijms20112684

Uterine leiomyoma is found in ~50-80% of women of a reproductive age and is the most common reason for hysterectomy. Recently, posttranscriptional gene silencing by microRNAs (miRs) has been reported as a mechanism for regulating gene expre…

lab-animal 2019
Molecular human reproduction ·doi:10.1093/molehr/gaz025

Aquaporins (AQPs) are involved in cell migration, proliferation and carcinogenesis in tumor development and physiologic inflammatory processes, but their associations with endometriosis have not been fully evaluated. In this study, tissue s…

other 2019
International journal of molecular sciences ·doi:10.3390/ijms20133372

Estrogen affects endometrial cellular proliferation by regulating the expression of the c-myc gene. B-cell translocation gene 1 (BTG1), a translocation partner of the c-myc, is a tumor suppressor gene that promotes apoptosis and negatively …

other 2018
Frontiers in endocrinology ·doi:10.3389/fendo.2018.00772

Background: Repair of DNA double strand break (DSB) is an important mechanism for maintaining genetic stability during a DNA damage event. Although, a growing body of recent evidence suggests that DNA DSBs and related repair mechanisms may …

lab-animal 2018
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117711263

Among the several components in Korean red ginseng, the saponin components are known to have various pharmacologic activities. The objective of this study was to evaluate therapeutic effects of saponin extracts from Korean red ginseng on en…

lab-animal 2017
Scientific reports ·doi:10.1038/s41598-017-17956-0

This research aimed to evaluate the potential therapeutic effects of Rg3 on endometriosis and identify target miRNAs. We designed an in vitro study using human endometrial stromal cells (HESCs) obtained from patients with endometriosis and …