Salama SA
No ORCID on file
· 3 papers in corpus
Ulipristal acetate (UPA) is effective in the treatment of uterine fibroids. However, its clinical use is hampered by the development of pathologic progesterone receptor modulator-associated endometrial changes (PAECs). The current study was…
ContextEstrogen and its metabolites play a critical role in the pathophysiology of the endometrium. The bioavailability of estrogen and estrogen metabolites in endometrial tissues depends on the expression of enzymes involved in estrogen bi…
ObjectiveTo investigate the role of catechol-O-methyl transferase (COMT) in the regulation of estrogen metabolism in human endometrium.DesignLaboratory study.SettingAcademic research laboratory.Intervention(s)Immunohistochemistry was used t…