Jan M. McAllister

ORCID: 0000-0002-6910-2801 · 2 papers in corpus

lab-animal 2012

Cholesterol side-chain cleavage gene expression in theca cells: augmented transcriptional regulation and mRNA stability in polycystic ovary syndrome

PloS one ·doi:10.1371/journal.pone.0048963

Hyperandrogenism is characteristic of women with polycystic ovary syndrome (PCOS). Ovarian theca cells isolated from PCOS follicles and maintained in long-term culture produce elevated levels of progestins and androgens compared to normal t…

2009

PDE8A Genetic Variation Is Not Associated with Polycystic Ovary Syndrome.

·doi:10.1093/biolreprod/81.s1.364

Polycystic ovary syndrome (PCOS) is characterized by excessive theca cell androgen secretion, dependent upon LH, which acts through the intermediacy of adenosine 3', 5'-cyclic monophosphate (cAMP). cAMP signaling pathways are controlled thr…