Sushma Marla

No ORCID on file · 4 papers in corpus · active 2020-2023

Study types

  • article 3
  • dissertation 1

Condition tags

  • endometriosis 4
  • endometrioma 1
  • die_deep_infiltrating 1
article 2023
Gene expression profiles separate endometriosis lesion subtypes and indicate a sensitivity of endometrioma to estrogen suppressive treatments through elevated ESR2 expression
BMC medicine ·doi:10.1186/s12916-023-03166-1

BACKGROUND: Endometriosis is a common, gynaecological disease characterised by the presence of endometrial-like cells growing outside the uterus. Lesions appear at multiple locations, present with variation in appearance, size and depth of …

article 2023
Global Analysis of Transcription Start Sites and Enhancers in Endometrial Stromal Cells and Differences Associated with Endometriosis
Cells ·doi:10.3390/cells12131736

Identifying tissue-specific molecular signatures of active regulatory elements is critical to understanding gene regulatory mechanisms. In this study, transcription start sites (TSS) and enhancers were identified using Cap analysis of gene …

dissertation 2023
Regulation of transcription in human endometrium and endometriosis
·doi:10.14264/fa4e077
article 2020
Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium
Molecular human reproduction ·doi:10.1093/molehr/gaaa082

The etiology and pathogenesis of endometriosis are complex with both genetic and environmental factors contributing to disease risk. Genome-wide association studies (GWAS) have identified multiple signals in the estrogen receptor 1 (ESR1) r…