Ishaq M

No ORCID on file · 2 papers in corpus

observational 2019

Association between Cyclooxygenase-2 and Indoleamine 2,3-Dioxygenase Expression in Breast Cancer Patients from Pakistan

Asian Pacific journal of cancer prevention : APJCP ·doi:10.31557/apjcp.2019.20.11.3521

BACKGROUND: Tumors use several immunosuppressive mechanisms to evade immune destruction. Cyclooxygenase-2 (COX-2) expression may be a driver of immunosuppression in breast cancer, but the mechanisms involved remain elusive. COX-2 expression…

lab-animal 2012

Gender differences in transcriptional signature of developing rat testes and ovaries following embryonic exposure to 2,3,7,8-TCDD

PloS one ·doi:10.1371/journal.pone.0040306

Dioxins are persistent organic pollutants interfering with endocrine systems and causing reproductive and developmental disorders. The objective of our project was to determine the impact of an in utero exposure to 2,3,7,8-tetrachlorodibenz…