Hernandez DG

No ORCID on file · 2 papers in corpus

2024

QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration.

Nature communications ·doi:10.1038/s41467-024-46063-8

DNA methylation provides a crucial epigenetic mark linking genetic variations to environmental influence. We have analyzed array-based DNA methylation profiles of 160 human retinas with co-measured RNA-seq and >8 million genetic variants, u…

2016

Menopause accelerates biological aging.

Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.1604558113

Although epigenetic processes have been linked to aging and disease in other systems, it is not yet known whether they relate to reproductive aging. Recently, we developed a highly accurate epigenetic biomarker of age (known as the "epigene…