Atwood CS

No ORCID on file · 4 papers in corpus
2024
Journal of Alzheimer's disease : JAD ·doi:10.3233/jad-240334

The increase in the incidence of dementia over the last century correlates strongly with the increases in post-reproductive lifespan during this time. As post-reproductive lifespan continues to increase it is likely that the incidence of de…

other 2021
Contemporary clinical trials ·doi:10.1016/j.cct.2021.106488

The LUCINDA Trial (Leuprolide plus Cholinesterase Inhibition to reduce Neurologic Decline in Alzheimer's) is a 52 week, randomized, placebo-controlled trial of leuprolide acetate (Eligard) in women with Alzheimer's disease (AD). Leuprolide …

2011
Journal of Alzheimer's disease : JAD ·doi:10.3233/jad-2011-110887

This commentary addresses a novel mechanism by which aging-related changes in reproductive hormones could mediate their action in the brain. It presents the evidence that dyotic endocrine signals modulate the expression of tumor necrosis fa…

review 2007
Expert opinion on investigational drugs ·doi:10.1517/13543784.16.11.1851

Leuprolide acetate is a synthetic nonapeptide that is a potent gonadotropin-releasing hormone receptor (GnRHR) agonist used for diverse clinical applications, including the treatment of prostate cancer, endometriosis, uterine fibroids, cent…