He JP

No ORCID on file · 3 papers in corpus
2024
Aberrant activated Notch1 promotes prostate enlargement driven by androgen signaling via disrupting mitochondrial function in mouse.
Cellular and molecular life sciences : CMLS ·doi:10.1007/s00018-024-05143-0

The prostate is a vital accessory gonad in the mammalian male reproductive system. With the ever-increasing proportion of the population over 60 years of age worldwide, the incidence of prostate diseases, such as benign prostatic hyperplasi…

2023
METTL3 is essential for normal progesterone signaling during embryo implantation via m6A-mediated translation control of progesterone receptor.
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2214684120

Embryo implantation, a crucial step in human reproduction, is tightly controlled by estrogen and progesterone (P4) via estrogen receptor alpha and progesterone receptor (PGR), respectively. Here, we report that N6-methyladenosine (m6A), the…

2021
Notch1 is crucial for decidualization and maintaining the first pregnancy in the mouse†.
Biology of reproduction ·doi:10.1093/biolre/ioaa222

The endometrium undergoes a pregnancy-delivery-repair cycle multiple times during the reproductive lifespan in females. Decidualization is one of the critical events for the success of this essential process. We have previously reported tha…