Phthalate esters (PAEs), frequently detected in various environmental media, are associated with multiple health issues, particularly reproductive toxicity. This study employed molecular docking and molecular dynamics simulations to investi…
BackgroundAdiposity profoundly impacts reproductive health in both humans and animals. However, the precise subpopulations contributing to infertility under obese conditions remain elusive.ResultsIn this study, we established an obese mouse…
BackgroundThe aim of this study was to develop a new model constructed by logistic regression for the early prediction of the severity of acute pancreatitis (AP) using magnetic resonance imaging (MRI) and the Acute Physiology and Chronic He…
Background Cardiometabolic diseases are highly comorbid and associated with poor health outcomes. However, the investigation of the relationship between the genetic predisposition to cardiometabolic diseases with the risk of conditions uniq…
Abstract Cardiometabolic diseases are highly comorbid, but their relationship with female-specific health conditions (breast cancer, endometriosis, pregnancy complications) is understudied. Using electronic health record data from 71,008 a…
PurposeChronic cholecystitis is a common inflammatory disease of the gallbladder. It is related with various gastrointestinal tumors, although its pathogenesis is not clear. This study was designed to investigate the association between chr…
BACKGROUND: To investigate the effectiveness of the GnRH-a ultra-long protocol, GnRH-a long protocol, and GnRH-a short protocol used in in vitro fertilization-embryo transfer (IVF-ET) in infertile women with endometriosis. METHODS: We searc…
Endometriosis affects women of reproductive age via unclear immunological mechanism(s). Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of myeloid cells with potent immunosuppressive and angiogenic properties. Here, we fo…