G. C. M. L. Christiaens

Prostaglandin synthesis inhibitors decrease menstrual blood loss by 30% to 50% in patients with essential menorrhagia. To obtain insight into their mechanism of action, we measured menstrual blood loss in menorrhagic women, who were receivi…

Light microscopy, electron microscopy and immunofluorescence were used to study the endometrium from nine uteri removed during the first 72 hours of normal menstruation. During premenstrual spotting, stromal disintegration and vessel lesion…