C Kakinuma

No ORCID on file · 3 papers in corpus
lab-animal 2017
Effect of Genistein, Leuprolide Acetate and Dienogest towards Progesterone Receptor, IL-8, MMP-2 Expression of Lesions in a Peritoneal Mice Model of Endometriosis
·doi:10.20902/ijptr.2018.11110

Endometriosis is estrogen-dependent disease that is related to the inflammatory process in the peritoneal cavity. To being activated by pro-inflammatory cytokines, endometriosis is also influenced by the response of progesterone receptors. …

lab-animal 2000
Growth-stimulating effect of dienogest, a synthetic steroid, on rodent, canine, and primate mammary glands
Toxicology ·doi:10.1016/s0300-483x(00)00318-8

We observed hyperplasia of the mammary gland in female beagle dogs, but not in female rats and monkeys, in 91-day toxicity studies on dienogest. In order to elucidate a possible mechanism for its development and to account for this species …

lab-animal 1994
Successful heterotransplantation of human endometrium in SCID mice
Obstetrics & Gynecology

OBJECTIVE: To establish an experimental system useful for long-term evaluation of human endometrial tissue by its heterotransplantation to SCID mice. METHODS: Human endometrium was transplanted subcutaneously into SCID mice, nude mice, or …