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Importance Colporrhaphy is a surgical option for anterior or posterior compartment vaginal prolapse. Colporrhaphy has a high complication rate. Previous literature proved that individuals diagnosed with diabetes had higher rates of complica…

Introduction Pelvic organ prolapse (POP) is a very common concern for women that can often necessitate surgical intervention, including sacral colpopexy. There are multiple surgical approaches, including vaginal, extraperitoneal, and intrap…

Silent information regulator type 1 (SIRT1), a NAD+-dependent deacetylase, is a central regulator of cancer cell adaptation to oxidative stress and senescence. By deacetylating redox-sensitive transcription factors, such as p53, FOXOs, PGC-…