Holdsworth-Carson S

No ORCID on file · 4 papers in corpus
article 2026
Endometriosis Longitudinal Fertility Study (ELFS): a prospective longitudinal cohort study of the effect of conservative and surgical management for moderate to severe endometriosis on future fertility - study protocol
BMJ open ·doi:10.1136/bmjopen-2025-114124

INTRODUCTION: Endometriosis is associated with reduced pregnancy and live birth rates in patients attempting both spontaneous and assisted conception. At present, it is unclear whether prepregnancy surgery for moderate or severe endometrios…

meta-analysis 2026
Fertility after endometriosis surgery: a systematic review and meta-analysis comparison of primary versus multiple surgical interventions
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2026.115011

Symptoms of endometriosis are often incompletely managed and recurrent surgeries are commonplace. The impact of re-operation on fertility remains unclear. This systematic review compares fertility outcomes in patients who underwent primary …

preprint 2025
Mathematical modelling of macrophage and natural killer cell immune response during early stages of peritoneal endometriosis lesion onset
·doi:10.1101/2025.01.20.633967

Abstract The immune system is hypothesised to contribute to the onset of endometriosis lesions. However, the precise mechanisms underlying its role are not yet known. We introduce a novel compartmental model that describes the interactions …

article 2025
Mathematical modelling of macrophage and natural killer cell immune response during early stages of peritoneal endometriosis lesion onset
Journal of the Royal Society, Interface ·doi:10.1098/rsif.2025.0076

The immune system is hypothesized to contribute to the onset of endometriosis lesions. However, the precise mechanisms underlying its role are not yet known. We introduce a novel compartmental model that describes the interactions between i…