Endometriosis is an estrogen-dependent disease defined by the presence and growth of functional endometrial-like tissue, glands and stroma, outside the uterine cavity. Macrophages are broadly classified into pro-inflammatory M1 macrophages,…
Endometriosis is a common benign and proliferative chronic disorder, characterized by the presence of endometrial glands and stroma outside the uterus: in particular, ectopic endometrial tissue und...
PurposeTo evaluate reproductive and maternal-fetal outcomes after integrated approach for endometriosis-associated infertility (EAI).MethodsWe retrospectively analyzed reproductive and maternal-fetal outcomes of 277 women affected by EAI, s…
The theory of retrograde menstruation as aetiopathogenesis of endometriosis formulated by John Sampson in 1927 shows clear shortcomings: this does not explain why retrograde menstruation is a physiological process that affects 90% of women,…