Spector TD

No ORCID on file · 11 papers in corpus
2024
Human reproduction (Oxford, England) ·doi:10.1093/humrep/dead247

Study questionWhich genetic factors regulate female propensity for giving birth to spontaneous dizygotic (DZ) twins?Summary answerWe identified four new loci, GNRH1, FSHR, ZFPM1, and IPO8, in addition to previously identified loci, FSHB and…

2019
Nature genetics ·doi:10.1038/s41588-019-0447-2

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

2018
Nature genetics ·doi:10.1038/s41588-017-0011-x

Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which pinpointing causal gene…

2018
Nature genetics ·doi:10.1038/s41588-018-0082-3

In the version of this article originally published, one of the two authors with the name Wei Zhao was omitted from the author list and the affiliations for both authors were assigned to the single Wei Zhao in the author list. In addition, …

2018
Nature genetics ·doi:10.1038/s41588-018-0050-y

In the published version of this paper, the name of author Emanuele Di Angelantonio was misspelled. This error has now been corrected in the HTML and PDF versions of the article.

2016
Nature genetics ·doi:10.1038/ng.3698

The genetic architecture of human reproductive behavior-age at first birth (AFB) and number of children ever born (NEB)-has a strong relationship with fitness, human development, infertility and risk of neuropsychiatric disorders. However, …

2016
European journal of human genetics : EJHG ·doi:10.1038/ejhg.2015.102

Genetic factors contribute strongly to sex hormone levels, yet knowledge of the regulatory mechanisms remains incomplete. Genome-wide association studies (GWAS) have identified only a small number of loci associated with sex hormone levels,…

2015
Nature ·doi:10.1038/nature14132

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links…

2013
Journal of the National Cancer Institute ·doi:10.1093/jnci/djt303

BackgroundEsophageal adenocarcinoma (EA) is an increasingly common cancer with poor survival. Barrett's esophagus (BE) is the main precursor to EA, and every year 0.12% to 0.5% of BE patients progress to EA. BE typically arises on a backgro…

2012
PloS one ·doi:10.1371/journal.pone.0035041

BackgroundFemale sexual dysfunction (FSD) is an important but controversial problem with serious negative impact on women's quality of life. Data from twin studies have shown a genetic contribution to the development and maintenance of FSD.…

2008
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2007-2568

ContextAge at menarche (AAM) is an important trait both biologically and socially, a clearly defined event in female pubertal development, and has been associated with many clinically significant phenotypes.ObjectiveThe objective of the stu…