Langoi D

No ORCID on file · 4 papers in corpus
article 2012
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.11.021

ObjectiveTo determine the effect of inhibiting aromatase activity on endometrial lesion growth and aromatase expression in a baboon model of induced endometriosis.DesignProspective study.SettingPrimate research institute.Animal(s)Sixteen ol…

review 2005
Pharmacological reviews ·doi:10.1124/pr.57.3.6

A single gene encodes the key enzyme for estrogen biosynthesis termed aromatase, inhibition of which effectively eliminates estrogen production. Aromatase inhibitors successfully treat breast cancer and endometriosis, whereas their roles in…

review 2004
Seminars in reproductive medicine ·doi:10.1055/s-2004-823026

Aromatase p450 (p450arom) is the key enzyme for biosynthesis of estrogen, which is an essential hormone for the establishment and growth of endometriosis. There is no detectable aromatase enzyme activity in normal endometrium; therefore, es…

article 2003
Fertility and sterility ·doi:10.1016/s0015-0282(03)00982-8

ObjectiveTo evaluate steroid receptor and aromatase gene expression in endometriotic lesions, and determine the effects of endometriosis on uterine receptivity in a baboon model for endometriosis.DesignProspective study to determine the exp…