Lopez-Berestein G

No ORCID on file · 2 papers in corpus

2019

PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis.

EBioMedicine ·doi:10.1016/j.ebiom.2018.11.045

BackgroundInflammatory mediator prostaglandin E2-prostaglandin E2 receptor EP3 (PTGER3) signaling is critical for tumor-associated angiogenesis, tumor growth, and chemoresistance. However, the mechanism underlying these effects in ovarian c…

2011

Identification of novel therapeutic targets in microdissected clear cell ovarian cancers.

PloS one ·doi:10.1371/journal.pone.0021121

Clear cell ovarian cancer is an epithelial ovarian cancer histotype that is less responsive to chemotherapy and carries poorer prognosis than serous and endometrioid histotypes. Despite this, patients with these tumors are treated in a simi…