Snyder CWA

No ORCID on file · 2 papers in corpus

2024

The NF-κB-HE4 axis: A novel regulator of HE4 secretion in ovarian cancer.

PloS one ·doi:10.1371/journal.pone.0314564

Ovarian cancer is the leading cause of death among gynecologic malignancies. Despite recent advancements in targeted therapies such as PARP inhibitors, recurrence is common and frequently resistant to existing therapies. A powerful diagnost…

2022

Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors In Vivo.

Journal of medicinal chemistry ·doi:10.1021/acs.jmedchem.1c01878

Vitamin-D receptor (VDR) mRNA is overexpressed in neuroblastoma and carcinomas of lung, pancreas, and ovaries and predicts poor prognoses. VDR antagonists may be able to inhibit tumors that overexpress VDR. However, the current antagonists …