Hartmann LC

No ORCID on file · 4 papers in corpus
other 2015
Nucleic acids research ·doi:10.1093/nar/gkv111

To determine early somatic changes in high-grade serous ovarian cancer (HGSOC), we performed whole genome sequencing on a rare collection of 16 low stage HGSOCs. The majority showed extensive structural alterations (one had an ultramutated …

other 2013
Human molecular genetics ·doi:10.1093/hmg/ddt160

Ovarian cancer remains the leading cause of death in women with gynecologic malignancies, despite surgical advances and the development of more effective chemotherapeutics. As increasing evidence indicates that clear-cell ovarian cancer may…

other 2009
PloS one ·doi:10.1371/journal.pone.0006292

BACKGROUND: Despite low incidence, ovarian cancer is the fifth leading cause of cancer deaths and it has the highest mortality rate of all gynecologic malignancies among US women. The mortality rate would be reduced with an early detection …

other 2008
International journal of cancer ·doi:10.1002/ijc.23717

Quantitation of circulating tumor cells (CTCs) can provide information on the stage of a malignancy, onset of disease progression and response to therapy. In an effort to more accurately quantitate CTCs, we have synthesized fluorescent conj…