Alexandra M Gouveia

No ORCID on file · 2 papers in corpus

other 2025

Metformin reverses infertility in a mouse model of endometriosis: unveiling disease pathways and implications for future clinical approaches

Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2024.104474

RESEARCH QUESTION: Does metformin reverse endometriosis-associated infertility? DESIGN: Endometriosis was induced by transplanting uterus fragments from B6CBAF1 mice into recipients of the same strain. The mice were divided into groups: en…

article 2022

Anti-oxidant effect of metformin through AMPK/SIRT1/PGC-1α/SIRT3- independent GPx1 expression in the heart of mice with endometriosis

Hormone molecular biology and clinical investigation ·doi:10.1515/hmbci-2022-0039

OBJECTIVES: Endometriosis is a gynecological disease associated with an imbalance between oxidative species production and anti-oxidative defenses. In women, endometriosis has been reported to associate with increased incidence of cardiovas…