BACKGROUND: The surgical management of endometrioma(s) remains challenging. Although laparoscopic surgery is a well-established treatment of endometrioma(s), caution is required to minimize ovarian damage. Several surgical techniques have b…
INTRODUCTION: Surgery is the cornerstone of ovarian cancer treatment. However, surgery and perioperative inflammation have been described as potentially pro-metastagenic. In various animal models and other human cancers, intraoperative admi…
Estrogens play a critical role in the pathogenesis of endometriosis and it is logical to assume that lowering estradiol levels with oral gonadotropin-releasing hormone (GnRH) antagonists may prove effective, especially in women who fail to …
Jacques Donnez,1,2 Luciana Cacciottola,3 Jean-Luc Squifflet,4 Marie-Madeleine Dolmans3,4 1Department of Gynaecology, Université Catholique de Louvain, Brussels, Belgium; 2Société de Recherche pour l’Infertilité (SRI), Brussels, Belgium; 3Gy…
Objective: To describe the available knowledge on vulvo-perineal endometriosis including its diagnosis, clinical management and recurrence rate. Methods: We followed the PRISMA guidelines for Systematic Reviews and our study was prospective…
OBJECTIVE: To study the mechanisms of invasion and innervation of deep endometriosis in women. DESIGN: Morphologic and immunohistochemical analysis of human endometriotic lesions. SETTING: Academic research unit. PATIENT(S): Seventeen bi…