Soucek P

IntroductionOvarian cancer (OC) represents a serious disease with high mortality and lack of efficient predictive and prognostic biomarkers. ATP-binding cassette (ABC) proteins constitute a large family dedicated to active transmembrane tra…

Objectives Current findings in the biology of tumors and also new tools for genome analysis have opened clinical perspectives in oncology, generally termed as ‘personalized medicine’. Pharmacogenomics examines how the benefits and adverse e…